Hepatocellular carcinoma in the 3rd millennium / Massimiliano Berretta and Bruno Cacopardo, editors.

Includes bibliographical references and index.

Description based on print version record and CIP data provided by publisher.

HEPATOCELLULAR CARCINOMA IN THE 3RD MILLENNIUM ; HEPATOCELLULAR CARCINOMA IN THE 3RD MILLENNIUM ; Library of Congress Cataloging-in-Publication Data; CONTENTS ; PREFACE ; Chapter 1 THE EPIDEMIOLOGY OF HEPATOCELLULAR CARCINOMA ; ABSTRACT ; INTRODUCTION ; PRIMARY LIVER CANCER: A GLOBAL EPIDEMIOLOGICAL OVERVIEW ; FOCUS ON WESTERN COUNTRIES: INCIDENCE AND MORTALITY RATES IN THE US AND EUROPE ; THE EPIDEMIOLOGY OF RISK FACTORS FOR HCC ; CONCLUSION ; REFERENCES ; Chapter 2 RISK FACTORS FOR HEPATOCELLULAR CARCINOMA ; ABSTRACT ; INTRODUCTION ; CHRONIC VIRAL HEPATITIS ; ALCOHOL

NON-ALCOHOLIC FATTY LIVER DISEASE OTHER RISK FACTORS ; CONCLUSION ; REFERENCES ; Chapter 3 HEPATOCELLULAR CARCINOMA GENETIC LANDSCAPE; ABSTRACT; INTRODUCTION; HISTOPATHOLOGICAL CARCINOGENESIS: AN OVERVIEW ; WNT PATHWAY ; DNA INTEGRITY AND CELL CYCLE CONTROL ; CHROMATIN REMODELING ; RAS AND PI3K SIGNALING ; OXIDATIVE STRESS RESPONSE PATHWAY ; DIFFERENTIATION AND DEVELOPMENT ; CONCLUSION ; REFERENCES ; Chapter 4 NON-INVASIVE DIAGNOSIS OF HEPATOCELLULAR CARCINOMA ; INTRODUCTION ; HEPATOCARCINOGENESIS ; ULTRASONOGRAPHY ; CONTRAST-ENHANCED ULTRASONOGRAPHY (CEUS) ; COMPUTED TOMOGRAPHY (CT)

MAGNETIC RESONANCE IMAGING (MRI) CONCLUSION ; REFERENCES ; Chapter 5 SCREENING AND SURVEILLANCE: HEPATOCELLULAR CARCINOMA ; ABSTRACT; INTRODUCTION ; TARGET POPULATION ; Screening and Surveillance Tests ; SURVEILLANCE INTERVAL ; RECALL POLICY ; FUTURE PERSPECTIVES ; CONCLUSION ; REFERENCES ; Chapter 6 PRIMARY PREVENTION OF HEPATOCELLULAR CARCINOMA ; ABSTRACT ; INTRODUCTION ; PREVENTION OF HBV-RELATED HCC ; PREVENTION OF HCV-RELATED HCC ; Other Strategies of Prevention ; REFERENCES ; Chapter 7 NATURAL HISTORY OF HEPATOCELLULAR CARCINOMA ; ABSTRACT; INTRODUCTION

THE TUMOR ASSOCIATED TO CHRONIC HEPATIC DISEASE EARLY TUMOR ; INTERMEDIATE TUMOR ; ADVANCED TUMOR ; TERMINAL TUMOR ; THE CAUSES OF DEATH ; THE PREDICTIVE FACTORS OF DEATH ; TUMOR ON HEALTHY LIVER ; FIBROLAMMELLAR CARCINOMA ; CONCLUSION ; REFERENCES ; Chapter 8 CLINICO-PATHOLOGICAL AND MOLECULAR FINDINGS IN HEPATOCELLULAR CARCINOMA ; ABSTRACT ; INTRODUCTION ; PATHOLOGY ; Surveillance and Clinical Aspects for Early Detection of HCC ; Nomenclature of Small Hepatocellular Nodules ; Small and Early HCC ; Small and Progressed HCC ; ROLE OF BIOPSY SAMPLING IN HCC DIAGNOSIS ; ADVANCED HCC

Macroscopic Morphology HISTOLOGY ; Special Types of HCC ; Recently Discovered Subtypes ; GRADING ; HCC VERSUS METASTATIC NEOPLASMS ; Immunoistochemistry ; OVERVIEW OF CURRENT HCC STAGING SYSTEMS ; TNM ; Okuda Score ; BCLC Staging Classification ; CLIP Score ; Japan Integrated Staging (JIS) ; Chinese University Prognostic Index (CUPI); Groupe d'Etude et de Traitement du Carcinome H�epatocellulaire (GRETCH) ; CLINICAL STAGING COMMENTS ; THERAPEUTIC MARKERS FOR HCC ; AKT and Wnt/B-Catenin Pathways ; p-RPS6 Protein and mTOR Pathway ; Expression Profiling ; Epigenetics ; Metabolomics ; CONCLUSION

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