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082 0 4 _a617.4/80592
_221
049 _aMAIN
100 1 _aFreed, William J.
_0http://id.loc.gov/authorities/names/n99800211
245 1 0 _aNeural transplantation :
_ban introduction /
_cWilliam J. Freed.
260 _aCambridge, Mass. :
_bMIT Press,
_c2000.
264 4 _c�2000
300 _a1 online resource (xii, 561 pages) :
_billustrations.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
_2rdacarrier
347 _adata file
_2rda
490 1 _aCellular and molecular neuroscience
500 _a"A Bradford book."
504 _aIncludes bibliographical references and index.
505 0 0 _g1.
_tIntroduction to transplantation in the nervous system --
_g2.
_tBrain structure and development --
_g3.
_tHistory of neural transplantation --
_g4.
_tTransplants and how they are used --
_g5.
_tControl groups and experiments --
_g6.
_tRegulations and guidelines for fetal tissue transplantation --
_g7.
_tMind control and other things to worry About --
_g8.
_tNeural systems and Parkinson's disease --
_g9.
_tNeural transplantation in Parkinson's disease : a brief synopsis --
_g10.
_tFetal brain tissue transplantation in Parkinson's disease : experiments in animals --
_g11.
_tAdrenal medulla transplantation --
_g12.
_tStudies in subhuman primates --
_g13.
_tFetal brain tissue transplantation in parkinson's disease : clinical studies --
_g14.
_tPain --
_g15.
_tHypothalamus and pituitary --
_g16.
_tThe cerebral cortex and stroke --
_g17.
_tHuntington's disease --
_g18.
_tSpinal cord --
_g19.
_tVisual system --
_g20.
_tIntroduction to genetic engineering and neural transplantation --
_g21.
_tGrowing cells in culture : stem and progenitor cells --
_g22.
_tGrowing cells in culture : immortal cell lines --
_g23.
_tGenetically modified cells for producing neurotrophic factors and neurotransmitters --
_g24.
_tDirect gene transfer --
_g25.
_tConclusions.
588 0 _aPrint version record.
520 8 _aAlthough there are many scientific and philosophical reasons to study the brain, for William J. Freed, "the most compelling reason to study the brain is to be able to repair the brains of individuals with nervous system injury or disease." Advances in repairing the nervous system, as well as new data on brain development, growth, and plasticity, have revolutionized the field of brain research and given rise to the technology of brain tissue transplantation. In this book Freed discusses both what may and what may not be possible. The book covers two aspects of neural tissue transplantation research. One involves the transplantation of particular cells to repair or augment specific neuronal systems. This technique could be useful for such conditions as Parkinson's disease, Huntington's disease, chronic pain, and epilepsy. The other line of research concerns regeneration from injury, especially of the spinal cord. After providing basic background on transplantation, brain structure, and development, the book discusses Parkinson's disease, the use of transplants to influence localized brain functions, circuit reconstruction, and genetic engineering and other future technologies.
546 _aEnglish.
590 _aeBooks on EBSCOhost
_bEBSCO eBook Subscription Academic Collection - Worldwide
650 0 _aNerve tissue
_xTransplantation
_xTechnique.
650 0 _aCentral nervous system
_xTransplantation.
650 0 _aIntracerebral transplantation.
_0http://id.loc.gov/authorities/subjects/sh92005956
650 1 2 _aBrain Tissue Transplantation.
650 6 _aTissu nerveux
_xGreffe
_xTechnique.
650 6 _aSyst�eme nerveux central
_xGreffe.
650 7 _aCentral nervous system
_xTransplantation.
_2fast
_0(OCoLC)fst00850755
650 7 _aIntracerebral transplantation.
_2fast
_0(OCoLC)fst00977743
655 0 _aElectronic books.
655 4 _aElectronic books.
776 0 8 _iPrint version:
_aFreed, William J.
_tNeural transplantation.
_dCambridge, Mass. : MIT Press, 2000
_z0262062089
_w(DLC) 99020115
_w(OCoLC)40939987
830 0 _aCellular and molecular neuroscience series.
_0http://id.loc.gov/authorities/names/n86723686
830 0 _aBradford book.
856 4 0 _uhttps://libproxy.firstcity.edu.my:8443/login?url=http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=21782
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