Cell transplantation : new research /
David J. Belgaris and Alyson N. Savarese, editors.
- 1 online resource : illustrations (some color).
- Cell biology research progress .
- Cell biology research progress. .
Includes bibliographical references and index.
CELL TRANSPLANTATION NEW RESEARCH ; CELL TRANSPLANTATION NEW RESEARCH ; Library of Congress Cataloging-in-Publication Data; Contents ; Preface ; Chapter I: Cell Transplantation in Chronic Kidney Disease ; Abstract ; 1. Introduction ; 2. Cell Source in Renal Regeneration ; 3. Cell Transplantation in Kidney Disease ; 4. Cell Transplantation for Renal Cell Carcinoma ; 5. Alternative Strategy in Cell Therapy of CKD ; Conclusion ; References ; Chapter II: Dendritic Cells in Allogeneic Hematopoietic Cell Transplantation ; Abstract; 1. Introduction 2. Phenotype and Classification of Dendritic Cells 3. Functional Classification of Dendritic Cells ; 4. Allogeneic Hematopoietic Cell Transplantation ; 4.1. Graft-Versus-Host Disease ; 4.2. Graft-Versus-Tumor Activity; 5. Role of Dendritic Cells in Graft-Versus-Host Disease ; 5.1. Role of Conventional Dendritic Cells in Graft-Versus-Host Diseases ; 5.2. Role of Plasmacytoid Dendritic Cells in Graft-Versus-Host Diseases ; 6. Potential Therapeutic Implications ; 6.1. Injection of Tolerogenic Dendritic Cells to Modify Conditioning Therapy Reducing Graft-Versus-Host Diseases 6.2. Combining Dendritic Cells with Vaccination to Reduce Graft-Versus-Host Disease While Preserving Graft-Versus-Tumor Activity 6.3. Potential Approaches Involving Conventional Dendritic Cells and Plasmacytoid Dendritic Cells to Reduce Graft-Versus-Host Diseases ; Conclusion; Acknowledgment ; References ; Chapter III: Chronic Graft Dysfunction in Allogeneic Islet Cell Transplantation; Abstract ; Introduction ; Current Status of Islet Transplantation ; Possible Mechanisms of Chronic Islet Graft Dysfunction; Late Acute Rejection; Allosensitization ; Recurrence of Autoimmunity Nonimmunological Factors Glucotoxicity to the Transplanted Islets ; Inflammatory Damage ; Amyloidosis ; Efforts to Overcome Chronic Islet Graft Dysfunction; Modification of Immunosuppression Protocol ; Supplemental Islet Transplantation ; Monitoring Islet Graft Function; SUITO Index ; Cluster Analysis of Self-Monitoring Blood Glucose ; Immune Monitoring ; Immune Monitoring for Allogeneic Rejection ; Immune Monitoring for Autoimmune Recurrence ; Antiinflammatory Strategy ; Conclusion ; Acknowledgment ; References ; Capter IV: Ocular Surface Reconstruction Using Cellular Therapies ; Abstract The Cornea and LimbusThe Limbal Stem Cell Niche ; Corneal Epithelial Renewal ; Limbal Stem Cell Deficiency ; Diagnosing Limbal Stem Cell Deficiency ; The Management of Limbal Stem Cell Deficiency ; Culture or Ex Vivo Expansion of Limbal Epithelium ; The Transplant Procedure ; Fate of the Donor Cells ; Conjunctival Epithelial Stem Cells and Conjunctival Stem Cell Deficiency ; Conclusion ; Acknowledgment ; References ; Chapter V: Cell Transplantation and Reconstructive Surgery ; Abstract; Introduction ; Bone Marrow-Derived Mesenchymal Stem Cells ; Endothelial Progenitor Cells
In this book, the authors gather and present topical research in the study of cell transplantation. Topics discussed in this compilation include cell transplantation in chronic kidney disease; dendritic cells in allogenic hematopoietic cell transplantation; islet cell transplantation replacing beta cells that produce insulin in a diabetes cure; ocular surface reconstruction using cellular therapies; cell therapy on ischemic flaps and new therapeutic strategy for veno-occlusive disease after hematopoietic stem cell transplantation.