TY  - BOOK
AU  - Catal�a,Angel
TI  - Membrane organization and lipid rafts in the cell and artificial membranes
T2  - Cell biology research progress
SN  - 9781634845892
AV  - QP752.M45 
U1  - 572/.577 23
PY  - 2016///
CY  - Hauppauge, New York
PB  - Nova Science Publishers, Inc.
KW  - Membrane lipids
KW  - Cell membranes
KW  - Membrane Lipids
KW  - SCIENCE
KW  - Life Sciences
KW  - Biochemistry
KW  - bisacsh
KW  - fast
KW  - Electronic books
N1  - Includes bibliographical references and index; MEMBRANE ORGANIZATION AND LIPID RAFTS IN THE CELL AND ARTIFICIAL MEMBRANES ; MEMBRANE ORGANIZATION AND LIPID RAFTS IN THE CELL AND ARTIFICIAL MEMBRANES ; Library of Congress Cataloging-in-Publication Data; CONTENTS ; PREFACE ; Chapter 1 FLUID -MOSAIC CELL MEMBRANE STRUCTURE: FROM CELLULAR CONTROL AND DOMAINS TO EXTRACELLULAR VESSICLES ; ABSTRACT ; ABBREVIATIONS ; INTRODUCTION ; CELL MEMBRANE PROPERTIES ; FLUID-MOSAIC MODEL OF CELL MEMBRANE STRUCTURE ; Membrane Cytoskeletal and Matrix Interactions ; Cell Membrane Protein and Lipid Interactions; Membrane Mobility Restrictions and Hierarchical Cell Membrane OrganizationMembrane Fusion and Membrane Vesicles ; Membrane Protusions from Normal and Tumor Cells ; Extracellular Vesicles and Exosomes ; FINAL COMMENT ; CONFLICT OF INTEREST ; ACKNOWLEDGMENTS ; REFERENCES ; Chapter2LIPIDRAFTSINBINARYLIPID/CHOLESTEROLBILAYERS; Abstract; 1. THERAFTCONCEPT; 2. DOMAINFORMATIONINMODELLIPIDMEMBRANES; 2.1. PhysicalPropertiesofLipids; 2.2. PhaseSeparationinMixed-ComponentModelLipidMembranes; 2.3. ModulatedPhasesandMicroemulsions; 3.X-RAYANDNEUTRONSCATTERINGEXPERIMENTSOFBINARYLIPID/CHOLESTEROLMEMBRANES; 3.1. StructureDeterminationbyDiffraction3.2. IdentificationofCholesterolPlaquesUsingX-RayDiffraction; 3.3. IdentificationofRaftsUsingNeutronDiffraction; 3.4. DynamicsofBinaryMixtures; 4. DRUGINTERACTIONSWITHMEMBRANEPATCHES; 5. ADDITIONALFRONTIERSINRAFTBIOPHYSICS; 6. CONCLUSION; Acknowledgments; References; Chapter 3 MEMBRANE ASSEMBLY AND LIPID RAFTS IN THE CELL AND ARTIFICIAL MEMBRANES: EFFECT OF LIPID PEROXIDATION ; ABSTRACT ; FLUID MOSAIC MODEL OF BIOLOGICAL MEMBRANE STRUCTURE ; LIPID RAFTS; BIOLOGICAL MEMBRANES IN CELLS ARE DIFFERENT FROM ARTIFICIAL MEMBRANES; THE DAMAGING EFFECTS OF LIPID PEROXIDATION ON MEMBRANE STRUCTURE AND FUNCTION THE LIPID PEROXIDATION PROCESS PRODUCES OXIDIZED PHOSPHOLIPIDS THAT ACQUIRE NEW BIOLOGICAL ACTIVITIES NOT CHARACTERISTIC OF THEIR UNOXIDIZED PRECURSORS ; THE CHANGES INDUCED BY LIPID PEROXIDATION IN MEMBRANE STRUCTURE AND DYNAMICS, BOTH AT THE LIPID AND PROTEIN LEVEL ; ACKNOWLEDGMENTS; REFERENCES; Chapter 4 DRUGS, DELIVERY SYSTEMS AND MEMBRANE ORGANIZATION IN MODEL AND CELL MEMBRANES ; ABSTRACT ; ABBREVIATIONS ; 1. INTRODUCTION ; 2. SPHINGOLIPIDS: METABOLISM, MEMBRANE ORGANIZATION AND CELL FUNCTION; 2.1. Sphingoid Bases2.2. Ceramide ; 2.3. Sphingomyelin; 2.4. GSLs ; 3. MEMBRANE ORGANIZATION AND CHEMOTHERAPEUTIC AGENTS ; 3.1. Modulation of Membrane Biophysical Properties by Chemotherapeutics ; 3.2. Membrane Properties-Dependent Antitumoral Agents ; 4. DELIVERY SYSTEMS ; 4.1. Dendrimers ; 4.2. Particulate Delivery Systems ; 4.2.1. Liposomes; 4.2.1.1. Ceramide-Containing Liposomes as Delivery Systems in Cancer Treatment ; 4.2.2. Other Particulate Delivery Systems ; CONCLUSION; REFERENCES
N2  - "This book presents an overview of membrane organization and lipid rafts in the cell and artificial membranes. The topics analyzed in this book cover a broad spectrum of functions played by lipid rafts in membrane organization within the cell and artificial membranes, and presents new information in this area of research. The topics analyzed include: fluid-mosaic cell membrane structure from cellular control and domains to extracellular vesicles; lipid rafts in binary lipid/cholesterol membranes; membrane assembly and lipid rafts in the cell and artificial membranes; the effect of lipid peroxidation; drugs, delivery systems and membrane organization in model and cell membranes; role of sphingomyelin on membrane domain formation and its influence in protein interaction focusing on the nanometer scale; lipid rafts and cell adhesion; mutual modulators of cell signaling; and finally, roles of glycosphingolipids in the regulation of the membrane organization and cell signaling in lipid rafts."--
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ER  -