Clinical applications of mifepristone (RU 486) and other antiprogestins :  assessing the science and recommending a research agenda / 
Committee on Antiprogestins: Assessing the Science, Division of Health Promotion and Disease Prevention, Institute of Medicine ; Molla S. Donaldson [and others], editors. 
 - Washington, D.C. :  National Academy Press,  1993. 
 - 1 online resource (xi, 288 pages) :  illustrations 
<br/><br/> "Support for this project was provided by a grant from the Henry J. Kaiser Family Foundation, Menlo Park, California."--Title page verso.  Committee chairman: Leslie Z. Benet. 
<br/><br/>Includes bibliographical references and index. 
<br/><br/>Background and historical perspectives -- IOM report -- Cross-cutting recommendations -- Uses of antiprogestins: the reproductive cycle -- Contraception -- Post-coital contraception -- Menses induction -- Uses of antiprogestins: the reproductive cycle -- Pregnancy termination during the first trimester -- Pregnancy termination during the second trimester -- Cervical ripening -- Labor induction in late pregnancy -- Other therapeutic uses of antiprogestins -- Endometriosis -- Uterine leiomyomas (fibroids) -- Breast cancer -- Meningiomas -- Antiglucocorticoid effects of antiprogestins -- Glucocorticoid function -- Therapeutic use of mifepristone (RU 486) as an antiglucocorticoid -- Adverse antiglucocorticoid effects of antiprogestins -- Animals as models for studying antiprogestins -- Agenda for the IOM workshop "Antiprogestins: Assessing the Science" -- Background papers and presentations (in order of presentation at IOM workshop) -- 1993: RU 486: a decade on today and tomorrow / Etienne-Emile Baulieu. (cont) Overview and background: mechanism of action of antiprogestins / Nancy L. Weigel -- Use of antiprogestins in the reproductive cycle / Lynnette Kaye Nieman -- Potential contraceptive effects of antigestogens / David T. Baird -- Use of antiprogestins before 63 days of amenorrhea / Marc Bygdeman -- Uses of antiprogestins after 63 days of amenorrhea / Ancre Ulmann and Louise Silvestre -- Comments on session II -- David Grimes -- Use of antiprogestins in the management of endometriosis and leiomyoma / Samuel S.C. Yen -- Antiprogestins and the treatment of breast cancer / Kathryn B. Horwitz -- Uses of RU 486 as an antiglucocorticoid / Lynnette Kaye Nieman -- Primate models for the study of antiprogestins in reproductive medicine / Gary D. Hodgen -- Antiprogestogens: perspectives from a global research program / P.F.A. Van Look and H. von Hertzen -- Observers at the workshop on antiprogestins. 
<br/><br/><br/>English. 
<br/><br/><label>ISBN: </label>0585024782 9780585024783 1280196025 9781280196027 9786610196029 6610196028 0309598354 9780309598354 
<br/><br/><label>LCCN: </label>
<br/><br/><label>Subjects--Topical Terms: </label><br/>Mifepristone--Research.<br/>Abortifacients--Research.<br/>Progesterone--Antagonists--Research.<br/>Mifepristone.<br/>Abortifacient Agents.<br/>Progesterone--antagonists & inhibitors.<br/>MEDICAL--Pharmacology.<br/>RU 486
<br/><br/><label>Index Terms--Genre/Form: </label><br/>Electronic book.<br/>Electronic books.
<br/><br/><label>LC Class. No.: </label>RG137.6.M53  / C57 1993eb 
<br/><br/><label>Dewey Class. No.: </label>615/.766 
<br/><br/><label>National Library of Medicine Call No.: </label>1994 B-064 QV 175 C641 1993